How to Remove a Wasps Nest Wasp nests can be particularly dangerous to resolve, an active nest can not be removed safely and will need some form of insecticide to be applied, There are many foams and powders available from most garden centres and hardware stores. Wasp and Fly Killer Fly and wasp killers are only suitable for a few insects you may have in the home, they are not for wasp nests. Never spray a colony with fly spray as it will agitate the wasps within the nest and will lead them to attack. Wasp Nest Destroyer Foam Wasp foams can be used to destroy a nest but great care needs to be taken. The only way a foam will work is if you cover the whole nest with the foam. To do this you need to get close to the nest, a few meters away and spray. I would always suggest to layer up well because foams do not kill instantly and things can often go wrong. Wasp Killer Powder Wasp powders are the best DIY products to use for wasp nests . Wasp